| Round | Type | Opponent | For | Against | Margin | Venue | Date | |
|---|---|---|---|---|---|---|---|---|
| R1 | Away | St Kilda | MCG | 20/03/2027 | ||||
| R2 | Away | Brisbane | Gabba | 25/03/2027 | ||||
| R3 | Home | Fremantle | MCG | 01/04/2027 | ||||
| R4 | Away | Sydney | Adelaide Oval | 09/04/2027 | ||||
| R5 | Away | Carlton | MCG | 15/04/2027 | ||||
| R6 | Home | Essendon | MCG | 25/04/2027 | ||||
| R7 | Away | West Coast | Perth Stadium | 01/05/2027 | ||||
| R8 | Home | Western Bulldogs | Docklands Stadium | 07/05/2027 | ||||
| R9 | Away | North Melbourne | Docklands Stadium | 16/05/2027 | ||||
| R10 | Home | Richmond | MCG | 22/05/2027 | ||||
| R11 | Away | Port Adelaide | Adelaide Oval | 29/05/2027 | ||||
| R12 | Home | Hawthorn | MCG | 04/06/2027 | ||||
| R13 | Away | Melbourne | MCG | 14/06/2027 | ||||
| R15 | Away | Gold Coast | Carrara Oval | 26/06/2027 | ||||
| R16 | Home | GWS Giants | MCG | 03/07/2027 | ||||
| R17 | Home | Brisbane | MCG | 05/07/2027 | ||||
| R18 | Home | Geelong | MCG | 12/07/2027 | ||||
| R19 | Away | Essendon | MCG | 19/07/2027 | ||||
| R20 | Away | Fremantle | Perth Stadium | 26/07/2027 | ||||
| R21 | Home | Carlton | MCG | 02/08/2027 | ||||
| R22 | Home | Adelaide | MCG | 09/08/2027 | ||||
| R23 | Home | St Kilda | Docklands Stadium | 16/08/2027 | ||||
| R24 | Away | Richmond | MCG | 23/08/2027 |