| Round | Type | Opponent | For | Against | Margin | Venue | Date | |
|---|---|---|---|---|---|---|---|---|
| R1 | Home | North Melbourne | 17.11 113 | 14.13 97 | 16 | Docklands Stadium | 15/03/2025 | Match stats |
| R2 | Home | Collingwood | 10.10 70 | 10.16 76 | -6 | MCG | 21/03/2025 | Match stats |
| R3 | Away | Carlton | 12.11 83 | 11.9 75 | 8 | Docklands Stadium | 28/03/2025 | Match stats |
| R4 | Away | Fremantle | Perth Stadium | 06/04/2025 | ||||
| R5 | Home | Brisbane | Norwood Oval | 12/04/2025 | ||||
| R6 | Home | St Kilda | Docklands Stadium | 20/04/2025 | ||||
| R7 | Away | GWS Giants | Manuka Oval | 26/04/2025 | ||||
| R8 | Home | Port Adelaide | Eureka Stadium | 03/05/2025 | ||||
| R9 | Away | Gold Coast | Marrara Oval | 10/05/2025 | ||||
| R10 | Home | Essendon | Docklands Stadium | 17/05/2025 | ||||
| R11 | Away | Geelong | Kardinia Park | 22/05/2025 | ||||
| R13 | Home | Hawthorn | Docklands Stadium | 05/06/2025 | ||||
| R14 | Away | St Kilda | Docklands Stadium | 12/06/2025 | ||||
| R15 | Home | Richmond | Docklands Stadium | 22/06/2025 | ||||
| R16 | Away | Sydney | SCG | 28/06/2025 | ||||
| R17 | Away | North Melbourne | Docklands Stadium | 04/07/2025 | ||||
| R18 | Home | Adelaide | Eureka Stadium | 11/07/2025 | ||||
| R19 | Away | Brisbane | Gabba | 18/07/2025 | ||||
| R20 | Away | Essendon | Docklands Stadium | 25/07/2025 | ||||
| R21 | Home | GWS Giants | Docklands Stadium | 01/08/2025 | ||||
| R22 | Away | Melbourne | MCG | 08/08/2025 | ||||
| R23 | Home | West Coast | Docklands Stadium | 15/08/2025 | ||||
| R24 | Home | Fremantle | Docklands Stadium | 22/08/2025 |