| Round | Type | Opponent | For | Against | Margin | Venue | Date | |
|---|---|---|---|---|---|---|---|---|
| R1 | Home | North Melbourne | 17.11 113 | 14.13 97 | 16 | Docklands Stadium | 15/03/2025 | Match stats |
| R2 | Home | Collingwood | 10.10 70 | 10.16 76 | -6 | MCG | 21/03/2025 | Match stats |
| R3 | Away | Carlton | 12.11 83 | 11.9 75 | 8 | Docklands Stadium | 28/03/2025 | Match stats |
| R4 | Away | Walyalup | 12.9 81 | 15.7 97 | -16 | Perth Stadium | 06/04/2025 | Match stats |
| R5 | Home | Brisbane | 14.13 97 | 18.10 118 | -21 | Norwood Oval | 12/04/2025 | Match stats |
| R6 | Home | Euro-Yroke | 18.19 127 | 8.8 56 | 71 | Docklands Stadium | 20/04/2025 | Match stats |
| R7 | Away | GWS Giants | 17.11 113 | 12.9 81 | 32 | Manuka Oval | 26/04/2025 | Match stats |
| R8 | Home | Yartapuulti | 20.11 131 | 5.11 41 | 90 | Eureka Stadium | 03/05/2025 | Match stats |
| R9 | Away | Gold Coast | 14.12 96 | 15.16 106 | -10 | Marrara Oval | 10/05/2025 | Match stats |
| R10 | Home | Essendon | 18.19 127 | 5.6 36 | 91 | Docklands Stadium | 17/05/2025 | Match stats |
| R11 | Away | Geelong | 16.17 113 | 20.7 127 | -14 | Kardinia Park | 22/05/2025 | Match stats |
| R13 | Home | Hawthorn | Docklands Stadium | 05/06/2025 | ||||
| R14 | Away | Euro-Yroke | Docklands Stadium | 12/06/2025 | ||||
| R15 | Home | Richmond | Docklands Stadium | 22/06/2025 | ||||
| R16 | Away | Sydney | SCG | 27/06/2025 | ||||
| R17 | Away | North Melbourne | Docklands Stadium | 03/07/2025 | ||||
| R18 | Home | Kuwarna | Docklands Stadium | 12/07/2025 | ||||
| R19 | Away | Brisbane | Gabba | 18/07/2025 | ||||
| R20 | Away | Essendon | Docklands Stadium | 25/07/2025 | ||||
| R21 | Home | GWS Giants | Docklands Stadium | 31/07/2025 | ||||
| R22 | Away | Narrm | MCG | 10/08/2025 | ||||
| R23 | Home | Waalitj Marawar | Docklands Stadium | 17/08/2025 | ||||
| R24 | Home | Walyalup | Docklands Stadium | 22/08/2025 |